MSCs are found as perivascular cells and, even in large vessels ,in the adventitia but, again, not in the generic connective tissue. To best understand the native, functional properties of MSCs, think PERICYTES.
Adipose is recognized to possess the greatest microvascular organ in the body. Many scientific papers suggest that adipose-derived (AD) stem/stromal cells of mesodermal origin provide between 1000 and 2500 times the actual numbers found in bone marrow. With the easy collection
of adipose tissue, less penetration, widely heterogeneous cellular populations, and important immune-privileged properties, subdermal fat deposits serve as a primary source for gathering stem/stromal cells.
The small adipose cells are found to be closely associated with the vascular tissues of our bodies. We recognize these cells as serving important roles in maintaining normal tissue content (homeostasis) plus having the ability to respond to injury or disease processes in a constant effort to heal or repair damaged cells.
The procedure takes up to 1 hour.
Adipose is readily available and safely accessible from the subdermal fat deposits found in the abdomen and thigh areas. These are gently removed via closed syringe lipoaspiration and then compressed by centrifugation.
Pre and Post injection protocols should be discussed with your doctor. However, having a healthy diet, being well hydrated, and active will help your recovery. Patients are generally able to resume normal activities within a few days.
Clinical trials are gradually being released, many requiring several years to acquire data, compile, and report. A vast majority of such reports are providing clear clinical evidence of patient safety and effective clinical treatment outcomes.
There are an estimated 150,000 human clinical uses and therapies in MSK applications. All with a remarkable efficacy and safety profile.
Immediately following an adipose procedure, your site of injection will probably be more sore than the harvesting location. The local anesthesia used wears off and pain relief medicine may be prescribed or recommended.