This is especially important when processing in a surgical suite. It is also proven to concentrate viable platelets, hematopoietic stem cells (HSC), total nucleated cells (TNC) and mesenchymal stem cells (MSC) in a bath of plasma with a low hematocrit. PureBMC® can be prepared with or without Heparin, either way it provides viable platelet concentrates that further add to the strength of the cell composition. PureBMC® delivers the excellence and reliability physicians can depend on. Higher HSC Concentrations Hematopoietic stem cells (HSCs) are the blood cells that have the ability to replenish all blood cell types (Multipotency) and the ability to self-renew. This include monocytes, macrophages, erythrocytes, megakaryocytes, platelets, neutrophils, basophils, eosinophils, dendritic cells and lymphoid lineage cells. Higher MSC Concentrations Mesenchymal stem cells (MSC) are multipotent stromal cells that can differentiate into a variety of cell types. These cell types primarily include cartilage, bone and adipose cells. Mesenchymal stem cells are found in very small quantities in bone marrow aspirate, making the concentrating capabilities of PureBMC® more vital to the physician. Higher TNC Concentrations Total nucleated cell count by any method is a count of cells with nuclei. In order to properly represent the TNC cell count a correction calculation that removes nucleated red blood cells (nRBCs) is performed. It is understood, as in other therapies, that more cells = better outcomes.

PureBMC® PureBMC® has been designed to improve performance outcomes. The design details allows the end user to more accurately collect high therapeutic cell concentrates with low red blood cell content. Same Great Outcomes Hematopoietic stem cells (CD34+), total nucleated cell (TNC), mesenchymal stem cell (CFU-F) and platelet isolation is perfected in the PureBMC® system. Similar to the Pure PRP®, PureBMC® is designed to retain high concentrations of these multiple cell concentrates with the lowest concentrations of red blood cells in a bone marrow concentrate product. Using a specialized cell isolation technique, PureBMC® provides more than 9X cell concentration in 7ml oaf PureBMC®. Preparation times are less than 10 minutes at the point of care. With careful attention to the details of gradient cell isolation, PureBMC® is a viable choice for a low hematocrit and high yielding bone marrow cell concentrate product.