PUREPRP®
SUPRAPHYSIOLOGIC
Unmatched Power & Versatility in Platelet Rich Plasma Formulation
- FDA-Registered Device
- Authorized Distributor
- Trusted by 1,000+ Clinics
Authorized Distributor
Direct from EmCyte Corporation
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Nationwide delivery available
Expert Support
Clinical training & education
Competitive Pricing
Best value on EmCyte products
Advanced Precision and Performance in Platelet Concentration
PurePRP® SupraPhysiologic is EmCyte Corporation’s proprietary platelet concentrating system engineered to deliver the highest concentrations of deliverable platelets at the point of care. As an authorized EmCyte distributor, AcCELLerated Biologics provides clinicians with direct access to this industry-leading technology.
Engineered for precision and versatility, this proprietary double-spin system allows physicians to customize PRP formulations and control the final treatment volume without compromising the biologic deliverables. It also provides the flexibility to produce neutrophil-rich or neutrophil-poor preparations tailored to each clinical application.
With an advanced, single-device design, PurePRP® SupraPhysiologic streamlines PRP preparation to under 10 minutes, ensuring consistent, predictable performance and optimized regenerative potential for superior patient outcomes.
Available in 30mL · 60mL · 120mL
Platelet Yield
Platelet Concentration
Hematocrit
Processing Time
PRP in Under 10 Minutes
PurePRP® SP’s streamlined double-spin process delivers consistent, predictable performance every time — with no additional equipment required.
Blood Draw
Draw whole blood (30–120mL depending on kit) into the proprietary anticoagulant tube.
First Spin
Centrifuge separates red blood cells from platelet-rich plasma in the bottom chamber.
Second Spin
The same single device performs a second spin, concentrating platelets to supraphysiologic levels
Customize
Selectively include or exclude neutrophils, adjust final volume based on treatment indication.
Inject
Deliver the highest-quality PRP at point of care — acid-free, autologous, and ready in under 10 minutes.
Neutrophils
Neutrophils in PurePRP® SupraPhysiologic
Neutrophils play a crucial role in Platelet-Rich Plasma (PRP) preparations, influencing both the inflammatory response and tissue regeneration. In neutrophil-rich PRP (nr-PRP), these immune cells contribute to early-phase inflammation, pathogen defense, and the release of growth factors that modulate healing.
Conversely, neutrophil-poor PRP (np-PRP) minimizes the inflammatory response, reducing the risk of excessive cytokine release, which may be beneficial in chronic conditions or delicate tissue applications. The choice between neutrophil-rich or neutrophil-poor PRP depends on the clinical application, balancing inflammation and regeneration to optimize patient outcomes.
Precision Neutrophil Isolation
PurePRP® SupraPhysiologic features advanced technology that precisely isolates neutrophils within the concentrating system, allowing for their selective extraction or retention based on clinical needs. This process ensures that platelet count and essential cellular mediators remain uncompromised, preserving the regenerative potential of the final PRP formulation.
Monocytes
Monocytes in PurePRP® SupraPhysiologic
Monocytes are unique immunoregulator cells that can sense, engulf, and kill bacteria, fungi, and parasites, helping to prevent the spread of infections. They differentiate into macrophages and dendritic cells, which are important for phagocytosis and antigen presentation, triggering adaptive immune responses.
Monocytes help regulate immunity against foreign substances, contributing to the overall health of the immune system. They can produce both pro- and anti-inflammatory cytokines, helping to modulate the inflammatory response and orchestrate optimal tissue repair.
Advanced Monocyte Enrichment
PurePRP® SupraPhysiologic is designed with advanced technology that selectively isolates high concentrations of monocytes in every PRP preparation, enhancing its immunomodulatory, antimicrobial, and regenerative properties. These monocytes play a critical role in orchestrating tissue repair, reducing excessive inflammation, and promoting an optimized healing environment for superior clinical outcomes.
Red Blood Cells
Red Blood Cells in PurePRP® SupraPhysiologic
The role of red blood cells (RBCs) in PRP formulation has been a subject of ongoing refinement. Excess RBC content has been associated with pro-inflammatory effects, oxidative stress, and potential cytotoxicity, all of which can impede the regenerative process. The breakdown of RBCs leads to the release of hemoglobin and iron, contributing to oxidative damage and inflammation that may counteract the healing benefits of PRP.
By reducing the RBC concentration, clinicians can mitigate these adverse effects, creating a more favorable microenvironment for tissue repair. However, a minimal presence of RBCs at low levels does not exert a deleterious effect — trace amounts may even play a supportive role by maintaining physiological oxygen levels in the local tissue environment, benefiting cellular metabolism and angiogenesis.
Monocytes help regulate immunity against foreign substances, contributing to the overall health of the immune system. They can produce both pro- and anti-inflammatory cytokines, helping to modulate the inflammatory response and orchestrate optimal tissue repair.
Precision RBC Removal — Over 99% Efficiency
PurePRP® SupraPhysiologic features advanced technology that efficiently removes over 99% of red blood cells while preserving clinically effective platelet concentrations in the final PRP sample. This optimized separation process enhances the regenerative potential of PRP by reducing unnecessary inflammatory byproducts while maintaining the biologic integrity of platelet-derived growth factors essential for healing.
Precision Cellular Engineering
PurePRP® SP doesn’t just concentrate platelets — it optimizes the entire cellular composition for maximum regenerative effect.
Platelets & Growth Factors
Platelets contain alpha granules packed with growth factors including PDGF, TGF-β, VEGF, and IGF-1. These growth factors drive cellular growth, differentiation, proliferation, and tissue healing. PurePRP® SP achieves 15× baseline platelet concentration — delivering the dosage the clinical literature identifies as therapeutically effective.
Monocytes & Immune Regulation
PurePRP® SP greatly enhances monocyte concentrations. Monocytes are unique immunoregulatory cells that sense, engulf, and kill bacteria, fungi, and parasites. They differentiate into macrophages and dendritic cells critical for phagocytosis and antigen presentation — providing powerful antimicrobial and regenerative support.
Neutrophil Flexibility: NR vs NP
Neutrophil-rich PRP (NR-PRP) contributes to early-phase inflammation, pathogen defense, and growth factor release — beneficial for some acute indications. Neutrophil-poor PRP (NP-PRP) bypasses inflammatory response, ideal for chronic degenerative conditions. PurePRP® SP is the only system that lets you choose either protocol in one device.
Cytokines & Cellular Mediators
Beyond platelets, PurePRP® SP preserves a rich environment of cytokines, signaling molecules, and hormones. These act as cellular messengers — binding to receptors on target cells, attracting regenerative cells, modulating immune response, and amplifying the healing cascade initiated by platelet growth factors.
It's All About Technology
PurePRP® SupraPhysiologic Concentrating Devices integrate a suite of proprietary technologies designed to optimize platelet isolation, cytokine enrichment, and overall PRP quality — delivering consistent, reproducible results every time.
Dynamic Chamber™
This innovation features two dynamically adaptive chambers within a single device, allowing precise isolation and selective collection of active cellular components using a double-spin technique. This ensures an optimal PRP formulation with unwanted components efficiently separated and removed.- Double-spin precision separation
- Selective cellular component collection
- Single-device simplicity
AspiraDome™
A groundbreaking advancement in platelet isolation and cytokine enrichment, AspiraDome enhances precision in cellular collection, ensuring that the PRP sample retains the highest concentrations of regenerative biofactors while eliminating unwanted cellular components.- Enhanced platelet isolation precision
- Maximum cytokine enrichment
- Eliminates unwanted cellular debris
BasePlane™
Designed with a flat base and larger surface area, this feature minimizes platelet clumping and premature activation while improving platelet resuspension. This ensures a more homogenous and effective PRP solution with consistent platelet distribution throughout the final product.- Minimizes platelet clumping
- Prevents premature activation
- Homogenous platelet distribution
Closed System Processing
Maintaining sterility throughout every stage of PRP preparation, the closed processing system eliminates contamination risks, ensuring safety, consistency, and compliance with medical standards. No environmental exposure at any point in the preparation process.- Zero environmental contamination
- Sterile throughout preparation
- Compliant with medical standards
What Sets PurePRP® SP Apart
Dual Dynamically Adaptive Chambers
Two chambers within a single device enable precise isolation and selective collection of active cellular components. The double-spin technique ensures an optimal PRP formulation with unwanted components removed — impossible with conventional systems.
AspiraDome™ Precision Collection
A groundbreaking advancement in platelet isolation and cytokine enrichment. AspiraDome's unique geometry enhances precision in cellular collection, ensuring the PRP retains the highest concentrations of regenerative biofactors while eliminating unwanted cellular debris.
Flat-Base Resuspension Platform
Designed with a flat base and larger surface area, this feature minimizes platelet clumping and premature activation while dramatically improving platelet resuspension quality — preserving regenerative potential until the moment of injection.
Selective Neutrophil Control
PurePRP® SP precisely isolates neutrophils within the concentrating system, allowing for their selective extraction or retention based on clinical needs. Platelet count and essential cellular mediators remain fully uncompromised.
Acid-Free Autologous Scope
Uniquely prepared within a special autologous scope that completely removes acidity without buffers or calcium activators. The result: clinical-grade PRP that is perfectly tolerated by patients, supporting the "No Burn Protocol" for comfortable injections.
Volume Control Without Compromise
Physicians can customize the final treatment volume without compromising biologic deliverables — a critical advantage when treating diverse anatomical targets requiring different injection volumes.
PurePRP® SP vs. Competing Systems
| Feature | PurePRP® SP (EmCyte) | Standard Double-Spin | Single-Spin Systems |
|---|---|---|---|
| Platelet Concentration | Up to 15× baseline | 5–8× baseline | Max 2× baseline |
| Platelet Recovery Rate | 90%+ | 60–75% | 40–55% |
| Single-Device Both Spins | ✓ | ✗ | ✗ |
| Neutrophil Protocol Flexibility | ✓ NR & NP | Limited | ✗ |
| AspiraDome™ Precision | ✓ | ✗ | ✗ |
| Acid-Free / No Burn Protocol | ✓ | ✗ | ✗ |
| Volume Customization | ✓ | Limited | ✗ |
| FDA 510(k) Cleared | ✓ | Varies | Varies |
| ISO Class 7 Manufacturing | ✓ | Varies | Varies |
| Prep Time | < 10 minutes | 15–25 minutes | 8–12 minutes |
PurePRP® SP — Choose Your System
30 mL
PurePRP® SP 30mL
- Blood Draw:30 mL
- PRP Output:3–7 mL customizable
- Platelet Yield:≥82%
- Processing:Under 10 minutes
- System:Double-spin, closed
Ideal for targeted, smaller-volume applications. Perfect for facial rejuvenation, hair restoration, and focused orthopedic injections.
60 mL
PurePRP® SP 60mL
- Blood Draw:60 mL
- PRP Output:5–15 mL customizable
- Platelet Yield:≥82%
- Processing:Under 10 minutes
- System:Double-spin, closed
The most versatile configuration. Ideal for orthopedic, sports medicine, and aesthetic applications requiring moderate-to-high PRP volumes.
120 mL
PurePRP® SP 120mL
- Blood Draw:120 mL
- PRP Output:10–20 mL customizable
- Platelet Yield:≥82%
- Processing:Under 10 minutes
- System:Double-spin, closed
Maximum volume for high-demand applications. Ideal for large joint injections, surgical augmentation, and multi-site treatments.
Where PurePRP® SP Delivers Results
Orthopedics & Sports Medicine
Knee OA, rotator cuff injuries, ACL/PCL repair augmentation, tendinopathy, and joint regeneration.
Regenerative Medicine
Tissue repair, wound healing, post-surgical recovery, and chronic pain management.
Aesthetic & Dermatology
Facial rejuvenation, hair restoration (androgenic alopecia), skin texture improvement, and scar treatment.
Spine & Pain Management
Epidural injections, facet joint treatment, disc regeneration, and chronic musculoskeletal pain.
Surgical Augmentation
Enhanced healing in surgical procedures, bone grafting, and post-operative tissue repair.
Wound Care
Chronic wound healing, diabetic ulcers, and accelerated tissue regeneration in complex wound management.
AcCELLerated Biologics — Your Premier EmCyte Distributor
As one of the nation’s leading authorized distributors of EmCyte regenerative medicine products, AcCELLerated Biologics provides clinicians with more than just product access. We deliver a complete ecosystem of support designed to help your practice thrive
Authorized & Verified
Direct partnership with EmCyte Corporation ensures you receive authentic, FDA-registered products with full manufacturer support.
Clinical Training & Education
Access to hands-on training courses, expert faculty, and advanced technique education to maximize your PRP outcomes.
Marketing & Practice Support
Comprehensive marketing materials, case studies, and practice-building resources to grow your regenerative medicine program.
Trusted by Elite Institutions
Products used at Cleveland Clinic, Yale, Stanford Health, Duke Health, Baylor College of Medicine, and 1,000+ practices nationwide.
Frequently Asked Questions
What is PurePRP® SupraPhysiologic (SP)?
PurePRP® SupraPhysiologic (SP) is EmCyte Corporation’s most advanced platelet-rich plasma concentrating system. It features a proprietary double-spin design with Dynamic Chamber™, AspiraDome™, and BasePlane™ technologies that deliver ≥82% platelet yield and the highest concentrations of deliverable platelets at the point of care in under 10 minutes.
How does PurePRP® SP differ from other PRP systems?
Where can I buy Emcyte PurePRP SP?
AcCELLerated Biologics is an authorized EmCyte distributor. You can request a quote or place an order by calling (800) 367-0844, emailing [email protected], or by submitting a quote request on our website.
What sizes does PurePRP® SupraPhysiologic come in?
Can PurePRP® SP produce both neutrophil-rich and neutrophil-poor PRP?
Is PurePRP® SP FDA-registered?
Do you offer training for PurePRP® SP?
What centrifuge is required for PurePRP® SP?
PurePRP® SP kits are fully compatible with all EmCyte centrifuge models — no additional equipment or modifications are required. If you are setting up a new practice or upgrading your centrifuge, contact our team at (800) 367-0844 and we’ll recommend the right configuration for your clinical volume. Learn more about our Executive Series Centrifuges here.
What kit size should I choose — 30mL, 60mL, or 120mL?
Does AcCELLerated Biologics offer training on PurePRP® SP?
Absolutely. As an authorized EmCyte distributor, AcCELLerated Biologics provides comprehensive onboarding, staff training, video tutorials, IFU guides, and access to our Regenerative Medicine Training Institute (RMTI). We also offer hands-on courses with small class sizes and expert faculty. Visit our Training & Resources section or call (800) 367-0844 to get started.
What is the “No Burn Protocol” and how does PurePRP® SP support it?
Resources
Founded in 1999 in Ft. Myers, EmCyte Corporation® is the global leader in platelet-rich plasma and progenitor stem cell biologics, dedicated to innovation that makes a clinical difference. Their proprietary product, PurePRP® SupraPhysiologic (PurePRP® SP), is a powerful autologous platelet-rich plasma used to treat and repair various injuries and conditions. PurePRP® SP stands out by providing a high concentration of deliverable regenerative cells while removing harmful factors, making it a preferred choice over surgery for many conditions. With over 20 years of experience, EmCyte continues to set the highest performance standards in regenerative medicine.
PurePRP® SupraPhysiologic Tutorials
